Yazar "Yiğit, Esra Nur" için listeleme
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Active shrinkage protects neurons following axonal transection
Aydın, Mehmet Şerif; Bay, Sadık; Yiğit, Esra Nur; Özgül, Cemil; Kaval Oğuz, Elif; Yenidünya Konuk, Elçin; Ayşit, Neşe; Cengiz, Nureddin; Erdoğan, Ender; Him, Aydın; Koçak, Mehmet; Eroğlu, Emrah; Öztürk, Gürkan (Elsevier Inc., 2023)Trauma, vascular events, or neurodegenerative processes can lead to axonal injury and eventual transection (axotomy). Neurons can survive axotomy, yet the underlying mechanisms are not fully understood. Excessive water ... -
Adult mouse dorsal root ganglia neurons form aberrant glutamatergic connections in dissociated cultures
Bayat, Fazlı Kemal; Polat Budak, Betül; Yiğit, Esra Nur; Öztürk, Gürkan; Gülçür, Halil Özcan; Güveniş, Albert (Public Library of Science, 2021)Cultured sensory neurons can exhibit complex activity patterns following stimulation in terms of increased excitability and interconnected responses of multiple neurons. Although these complex activity patterns suggest a ... -
A co-culture-based multiparametric imaging technique to dissect local H2O2 signals with targeted HyPer7
Seçilmiş, Melike; Altun, Hamza Yusuf; Pilic, Johannes; Erdoğan, Yusuf Ceyhun; Çokluk, Zeynep; Ata, Büşra Nur; Sevimli, Gülşah; Zaki, Asal Ghaffari; Yiğit, Esra Nur; Öztürk, Gürkan; Malli, Roland; Eroğlu, Emrah (MDPI, 2021)Multispectral live-cell imaging is an informative approach that permits detecting biological processes simultaneously in the spatial and temporal domain by exploiting spectrally distinct biosensors. However, the combination ... -
Comparison of the efficiencies of intrathecal and intraganglionic injections in mouse dorsal root ganglion
Aydın, Mehmet Şerif; Yiğit, Esra Nur (Turkiye Klinikleri, 2023)Background/aim: Dorsal root ganglia (DRG) are structures containing primary sensory neurons. Intraganglionic (IG) and intrathecal (IT) applications are the most common methods used for viral vector transfer to DRG. We aim ... -
Development of a chemogenetic approach to manipulate intracellular pH
Zaki, Asal Ghaffari; Miri, Seyed Mohammad; Çimen, Şeyma; Akgül Çağlar, Tuba; Yiğit, Esra Nur; Aydın, Mehmet S.; Öztürk, Gürkan; Eroğlu, Emrah (American Chemical Society, 2023)Chemogenetic Operation of iNTRacellular prOton Levels(pH-Control)is a novel substrate-based enzymatic method that enables precise spatiotemporalcontrol of ultralocal acidification in cultured cell lines and primaryneurons. ... -
Expression of Pea3 protein subfamily members in hippocampus and potential regulation following neuronal stimulation
Kandemir, Başak; Davis, Sabrina; Yiğit, Esra Nur; Öztürk, Gürkan; Yılmaz, Bayram; Laroche, Serge; Aksan Kurnaz, Işıl (Elsevier Ireland Ltd, 2020)Pea3 proteins belong to a subfamily of the E-twentysix (ETS) domain superfamily of transcription factors, which play various roles during development. Polyoma Enhancer-Activator 3 (Pea3) proteins Pea3, ERM and Er81 are ... -
The protective effect of platelet-rich plasma administrated on ovarian function in female rats with Cy-induced ovarian damage
Özcan, Pınar; Takmaz, Taha; Tok, Olgu Enis; İşlek, Sevde; Yiğit, Esra Nur; Fıçıcıoğlu, Cem (Springer, 2020)Purpose We evaluated the protective effect of PRP on ovarian function in female rats with cyclophosphamide (Cy)-induced ovarian damage. Methods Thirty-two adult female Sprague-Dawley rats were randomly divided into four ... -
A transcriptome based approach to predict candidate drug targets and drugs for Parkinson's disease using an in vitro 6-OHDA model
Yiğit, Esra Nur; Sönmez, Ekin; Yüksel, İsa; Aksan Kurnaz, Işıl; Çakır, Tunahan (Royal Society of Chemistry, 2023)The most common treatment strategies for Parkinson's disease (PD) aim to slow down the neurodegeneration process or control the symptoms. In this study, using an in vitro PD model we carried out a transcriptome-based drug ... -
Transfer and integration of breast milk stem cells to the brain of suckling pups
Aydın, Mehmet Şerif; Yiğit, Esra Nur; Vatandaşlar, Emre; Erdoğan, Ender; Öztürk, Gürkan (Nature Publishing Group, 2018)Beside its unique nutritional content breast milk also contains live cells from the mother. Fate of these cells in the offspring has not been adequately described. In this study, we aimed to detect and identify maternal ... -
Transnöronal dejenerasyonun hücre kültüründe canlı görüntüleme yöntemi ile araştırılması
Yiğit, Esra Nur (İstanbul Medipol Üniversitesi Sağlık Bilimleri Enstitüsü, 2017)Sinir sisteminde kısıtlı bir alanda meydana gelen bir hasar öncelikle hasar bölgesindeki hücreleri etkiler ve sonrasında çevre bölgelerde ikincil hasar diye de adlandırılan patolojik bir sürecin başlamasına sebep olur. ...